Urothelial progenitor cells: regional differences in the rat bladder
نویسندگان
چکیده
منابع مشابه
Label-retaining cells of the bladder: candidate urothelial stem cells.
Adult tissue stem cells replicate infrequently, retaining DNA nucleotide label (BrdU) for much longer periods than mature, dividing cells in which the label is diluted during a chase period. Those "label-retaining cells" (LRCs) have been identified as the tissue stem cells in skin, cornea, intestine, and prostate. However, in the urinary tract uroepithelial stem cells have not yet been identifi...
متن کاملEvidence for and against regional differences in neural stem and progenitor cells of the CNS.
Neural stem and progenitor cells (NSCs) give rise to the cellular diversity of the CNS. There is evidence both for and against differences in these cells based on the region of the brain in which they reside. Primary brain tumors mimic many aspects of NSC behavior. Recent data suggest that some of the variability in glioma biology may be, in part, a reflection of regional differences in the NSC...
متن کاملBeta-adrenoceptor agonists stimulate endothelial nitric oxide synthase in rat urinary bladder urothelial cells.
We have investigated the intracellular signaling mechanisms underlying the release of nitric oxide (NO) evoked by beta-adrenoceptor (AR) agonists in urinary bladder strips and cultured bladder urothelial cells from adult rats. Reverse transcription-PCR revealed that inducible NO synthase and endothelial NOS but not neuronal NOS genes were expressed in urothelial cells. NO release from both urot...
متن کاملEffects of curcumin on bladder cancer cells and development of urothelial tumors in a rat bladder carcinogenesis model.
Curcumin, a well-known dietary pigment derived from Curcuma longa, inhibited growth of several types of malignant cells both in vivo and in vitro. Its effects on cell proliferation and the induction of apoptosis in human bladder cancer cell lines and intravesical activity in a rat bladder tumor model were studied. Exposure of human bladder cancer cells to curcumin resulted in the induction of a...
متن کاملPODXL in urothelial bladder cancer
Bladder cancer is a heterogenous disease, ranging from minimally invasive, low-grade tumours with low recurrence rates and mortality on one end of the spectrum, and muscle invasive, high-grade disease prone to recurrence, progression and death at the other end. The aim of this thesis was to investigate the expression, clinicopathological correlates and prognostic significance of the candidate b...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cell Proliferation
سال: 2007
ISSN: 0960-7722,1365-2184
DOI: 10.1111/j.1365-2184.2007.00424.x